Update: All lanes have been reopened.
Highway Patrol Troopers are investigating a crash on Highway 501 in Horry county, which closed south-bound lanes.
According to Highway Patrol's website, the crash happened around 8:15 pm, Wednesday. Injuries have been reported.
The crash happened on the bridge going over the Intracoastal Waterway.
WPDE NewsChannel 15 has a crew on the scene and we'll bring you more information as it becomes available.